| "Do not go where the path may lead, go instead where there is no path - and leave a trail." ~ Ralph Waldo Emerson ~ |
| Chemotherapy Drugs - Cisplatin |
| ORPHANS OF THE CANCER STORM |
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| What other names does this drug have? CDDP cisplatinum, Platinol What does it look like? A clear fluid. How is it given? Intravenous (IV) infusion. How does it work? Cisplatin is a platinating agent that inhibits DNA replication, RNA transcription, and protein synthesis. Are there any precautions? The child should drink lots of water or be given large amounts of IV fluids while receiving cisplatin to prevent damage to the kidneys. A diuretic drug, called Mannitol, may also given to decrease the risk of kidney damage. The child should be monitored for possible hearing loss. What are the common side effects? Nausea and vomiting Low blood counts (myelosuppression) Loss of appetite (anorexia) Loss of taste Hearing loss Tinnitus (ringing in the cars) Mineral imbalance Gout Kidney toxicity What are the infrequent side effects? Central nervous system toxicity Hypotension (low blood pressure) Tachycardia (fast heart rate) Color blindness Muscle weakness Poor co-ordination Liver toxicity For More information The British Columbia Cancer Agency has comprehensive patient and professionals info sheets about cisplatin. Go back to CHEMOTHERAPY main page. Go back to GENERAL TREATMENT index. Go back to ORbIT TREATMENT index. Go back to SONGS TREATMENT index. |
| Disclaimer This information page has been prepared by an individual who does not have medical training. However its contents have been reviewed by appropriately qualified medical professionals for accuracy and quality. This page is intended for information purposes only and should not be used as a guide to diagnosis or treatment. If this information raises any concerns about your child’s condition or care protocol, discuss them with his or her paediatrician, oncologist, or other appropriate medical professional who has knowledge of the case. |