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Chemotherapy Drugs - Temozolomide

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General Treatment Resource Centre
ORPHANS OF THE CANCER STORM
What other names does this drug have?

Temodar, Temodal, TMZ.


What does it look like?

A white capsule with a blue line, supplied in strengths of 5mg, 20mg, 100mg and 250mg.


How is it given?

The capsules should be swallowed whole with plenty of water and taken at the same time every day, on an empty stomach.


How does it work?

Temozolomide  is an alkylating agent which acts on DNA to prevent cell reproduction.


What are the common side effects?

Low blood cell counts (myelosuppression)
Nausea and vomiting
Loss of appetite (anorexia)
Constipation
Rash
Headache
Fatigue


What are the infrequent side effects?

Hair loss (alopecia)
Dizziness
Breathlessness


Additional information about temozolomide capsules.

- Store them at room temperature away from direct sunlight.
- It is important that you child take the capsules at the right times. You must give them as directed by the doctor.
- Keep the capsules in a safe place where children cannot reach them.
- If the doctor decides to stop treatment, return any remaining capsules to the pharmacist.  Do not flush them down the toilet or throw them away.
- If your child is sick just after taking the capsules,  let the doctor know as she may need to take another one.  Do not give another capsule without first telling the doctor.
- If you do forget to give a capsule, do not give a double dose. Tell the doctor and keep to your child's regular dose schedule.


For More information

The British Columbia Cancer Agency has comprehensive
patient and professionals info sheets about temozolomide.


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Disclaimer

This information page has been prepared by an individual who does not have medical training.  However its contents have been reviewed by appropriately qualified medical professionals for accuracy and quality.

This page is intended for information purposes only and should not be used as a guide to diagnosis or treatment. If this information raises any concerns about your child’s condition or care protocol, discuss them with his or her paediatrician, oncologist, or other appropriate medical professional who has knowledge of the case.
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