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Chemotherapy Drugs - Vincristine

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General Treatment Resource Centre
ORPHANS OF THE CANCER STORM
What other names does this drug have?

Oncovin, VCR.


What does it look like?

Vincristine is a clear fluid after being dissolved from powder


How is it given?

intravenous (IV) injection.


How does it works?

Vincristine is an alkaloid derived from the periwinkle plant that causes cells to stop dividing.


Are there any precautions?

Care should be taken to prevent leakage of vincristine from the IV site. The child may need to start on a program to prevent constipation.


What are the common side effects?

Constipation
Pain in jaw, face, back, joints, bones (may be severe)
Foot drop (child has trouble lifting front part of foot)
Peripheral neuropathy (numbing or tingling in fingers or toes)
Extreme weakness and loss of muscle mass
Blurred or double vision, drooping eyelids
Hair loss (alopecia)
Pain and blisters if drug leaks into tissues


What are the infrequent side effects?

Loss of appetite (anorexia)
Nausea and vomiting
Weight loss
Headaches,
dizziness,
lightheadedness
Convulsions
Difficulty urinating (dysuria)
Rash
Difficulty sleeping
Itchiness


For More information

The British Columbia Cancer Agency has comprehensive
patient and professionals info sheets about vincristine.



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Disclaimer

This information page has been prepared by an individual who does not have medical training.  However its contents have been reviewed by appropriately qualified medical professionals for accuracy and quality.

This page is intended for information purposes only and should not be used as a guide to diagnosis or treatment. If this information raises any concerns about your child’s condition or care protocol, discuss them with his or her paediatrician, oncologist, or other appropriate medical professional who has knowledge of the case.
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